targetSCREENER assays are based on the splitSENSOR technology. They are genetically encoded tools for cell-based high-throughput screening to monitor various cellular signalling events in living cells, either at the membrane or in the cytosol.
targetSCREENER assays are robust, sensitive, as well as quantitative, and offer flexible assay formats. They and have been applied to various drug targets including receptor tyrosine kinases and G protein-coupled receptors.
Below, select from a variety of targetSCREENER assays.